Mast cells are a type of immune cells in the human body which play a vital role in the progression of many diseases. They are involved in protective host immunity as the regulators.
Acupuncture is an effective analgesic therapy. Acupuncture points (acupoints) are characterized by a high density of subcutaneous mast cells (MCs); their activation has turned out to play a crucial role in the initiation of the analgesic effect.
Recent research has shown that subcutaneous mast cells are involved in the trigger mechanism of analgesia induced by acupuncture.
Skin mast cells are present at a high density in acupuncture points, and they are sensitive to mechanical stimulation. The enrichment of mast cells and the dense arrangement of collagen fibers, microvessels, and nerves form the basis for acupoints as the reaction sites of acupuncture.
Acupuncture manipulation activates the mast cells via the collagen network resulting in the migration, the aggregation, and the activation of mast cells. Acupuncture can cause the deformation of collagen fibers and activate TRPV channels on mast cells membrane, so as to stimulate mast cells to release bioactive substances and activate nerve receptors to generate analgesic effect.
Li-Na Wang et al Cells. 2022 Mar; 11(5): 809.
Yingchen Li et al Cells. 2022 Mar; 11(5): 860.
A leading acupuncture specialist in Chelsea, Kensington, Richmond London
Welcome to my blog, discover acupuncture with Dr Maggie Ju
Qualified as a medical doctor in Western medicine in China with a Medical degree from Beijing, China and a PhD degree from the UK. Many year research and clinical experiences. This blog is for information only.
Tuesday, 21 February 2023
How can acupuncture release pain? research updates.
Acupuncture can help to raise progesterone level to get pregnant.
In women progesterone is mainly made in the ovary. The production of progesterone is increasing rapidly after ovulation. Its level is highes...
Acupuncture helps improving foot drop Foot drop, sometimes called drop foot is a muscular weakness or paralysis that makes it difficult to ...
Acupuncture is used to various conditions such as fertility, low back pain and other pain conditions, facial treatment etc, however how acup...
Winter brings with its darker mornings and evenings, and some may feel they hardly see the sunlight at all---going to work in the dark and c...